The San Francisco 49ers are one of many hottest groups within the NFL after a 4-0 begin to the 2026 season, however their accidents have mounted week after week.
The Niners had accidents sustained to a couple gamers of their 24-14 win Sunday towards the Denver Broncos together with dropping Kyle Juszczyk to a knee harm.
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49ers head coach Kyle Shanahan instructed reporters in a convention name on Monday that Juszczyk had a “knee hyperextension with bone bruise” that might power him to sit down just a few weeks. With their 10-time Professional Bowl fullback briefly sidelined, Shanahan has begun to gameplan prospects for the subsequent man as much as fill his void.
“Yeah, (tight finish) Luke (Farrell) and Brayden (Willis) and (tight finish George) Kittle. They’re all fairly interchangeable, nevertheless it’ll positively get Brayden some extra ops,” Shanahan mentioned. “(Tight finish Jake) Tonges would do this for us final yr, the final couple of years, and misplaced him Week 1 and Brayden’s been prepared for this function.”
ANALYSIS: Winners and losers from 49ers’ win over Broncos
This is the most recent harm report for the 49ers:
49ers accidents updates
49ers head coach Kyle Shanahan supplied the most recent on a few of their injured gamers on the roster:
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Nick Bosa, DL
There was an replace on 49ers edge rusher Nick Bosa after he sustained a calf harm throughout warm-ups in Week 3.
Shanahan mentioned the 2022 NFL Defensive Participant of the Yr remains to be out along with his harm and “in all probability not anticipating to get (him) again this week.”
James Thompson, DL
One other defensive lineman acquired an replace from Shanahan. He instructed reporters Monday throughout a convention name that James Thompson will not be out there within the upcoming sport towards the Seattle Seahawks.
Thompson has dominated out with an ankle harm.
Mykel Williams, DE
Mykel Williams has been out recovering from a torn ACL harm suffered throughout Week 9 of the 2025 season. He was faraway from PUP listing on Sept. 30, signaling that Williams will quickly be out there to swimsuit up once more. He’s hopeful to be able to play towards the Seahawks in Week 5, Shanahan mentioned.
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“Mykel, hopefully follow retains going effectively, has a very good week of follow and hopefully we will get him activated on the finish of the week,” he mentioned. “However, it relies upon how the week goes.”
Marques Sigle, security
Marques Sigle suffered a excessive ankle sprain in San Francisco’s win. Sigle was injured on a kickoff return with 2:08 left within the sport towards the Broncos.
Sigle went to make a play on Broncos returner RJ Harvey going helmet first. After the play, Sigle remained on the turf as he was tended to by group medical workers. Sigle was helped on to his ft and he slowly walked to the locker room.
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Shanahan mentioned Sigle can be out however did not the size of his absence.
“Marques Sigle had a excessive ankle sprain,” Shanahan mentioned. “He’ll miss a while.”
Upton Stout, CB
Upton Stout was one other 49ers participant injured throughout Sunday’s win versus the Broncos. Shanahan instructed reporters after the sport that Stout had an AC sprain in his shoulder.
He supplied a timeline on Monday for Stout, alluding that the 24-year-old is questionable for Sunday.
“Upton Stout with a shoulder AC sprain. He’ll be day-to-day,” Shanahan mentioned. “We’ll need to handle him by means of the week to see if we will get him to Sunday.”
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This text initially appeared on USA TODAY: 49ers harm replace: Who will change Kyle Juszczyk in San Francisco?













